• Elevated glutamine triggers stroke risk in moyamoya disease via endothelial‐to‐mesenchymal transition, finds study
    on 18/04/2024 at 20:49

    A study appearing in MedComm has been led by Dr. Jizong Zhao, Dr. Dong Zhang, and Dr. Peicong Ge (Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University and Department of Neurosurgery, Beijing Hospital). The team presents a comprehensive investigation involving 360 adult MMD patients, finding that elevated serum glutamine levels were linked to increased stroke risk. Manipulation of integrin subunit beta 4 (ITGB4) and the use of atorvastatin was reported to alleviate the glutamine-induced EndMT, offering potential new therapeutic approaches for MMD.

  • Mitigating the risk of infection in combat-related injuries
    on 18/04/2024 at 20:47

    The severely invasive nature of combat trauma creates massive regions of injury, colonization and infection, requiring specialized diagnostic and aggressive therapeutic approaches. Previous reports indicate an estimated occurrence of wound infections in 18%–25% of combat-related injuries.

  • Researchers discover new therapeutic target for non-small cell lung cancer
    on 18/04/2024 at 20:43

    Non-small cell lung cancer accounts for nearly 85% of all lung cancer cases. Targeted immunotherapy is a common treatment, but it does not work for everyone. However, a new Moffitt Cancer Center study published in the journal Immunity offers insight into how lung cancer cells evade the protective immune system, potentially opening a door for novel antibody-based immunotherapies.

  • Gay and bisexual men diagnosed with mpox face substantial stigma, finds study
    on 18/04/2024 at 20:43

    Gay and bisexual men who were diagnosed with mpox (formerly known as monkeypox) during the 2022 outbreak in England faced substantial issues related to stigma and potentially poor-quality care when accessing services, finds a new study led by UCL researchers.

  • Reticulon 3 deficiency ameliorates post-myocardial infarction heart failure by alleviating mitochondrial dysfunction
    on 18/04/2024 at 20:33

    Heart failure (HF) after myocardial infarction (MI) is a global health issue with a high mortality rate. Multiple molecular mechanisms are involved in the development of HF after MI. However, interventions targeting these pathological processes alone remain clinically ineffective.

  • Newsom Offers a Compromise to Protect Indoor Workers from Heat
    by Samantha Young on 18/04/2024 at 23:15

    After rejecting proposed rules to protect millions of workers in sweltering warehouses, steamy kitchens, and other hot workplaces, California Gov. Gavin Newsom’s administration has offered a compromise to allow the protections to take effect this summer. But state and local correctional workers — and prisoners — would have to wait even longer.

  • Too Big To Fail? Now It’s ‘Too Big To Hack’
    on 18/04/2024 at 18:00

    Congress this week had the chance to formally air grievances over the cascading consequences of the Change Healthcare cyberattack, and lawmakers from both major parties agreed on one culprit: consolidation in health care. Plus, about a year after states began stripping people from their Medicaid rolls, a new survey shows nearly a quarter of adults who were disenrolled are now uninsured. Jessie Hellmann of CQ Roll Call, Sarah Karlin-Smith of the Pink Sheet, and Lauren Weber of The Washington Post join KFF Health News’ Mary Agnes Carey to discuss these stories and more. Also this week, KFF Health News’ Julie Rovner interviews Caroline Pearson of the Peterson Health Technology Institute.

  • The Path to a Better Tuberculosis Vaccine Runs Through Montana
    by Jim Robbins on 18/04/2024 at 09:00

    Researchers at the University of Montana have pitched in to develop a more effective vaccine in the fight against an ancient disease that still kills an estimated 1.6 million people a year worldwide.

  • Medicare’s Push To Improve Chronic Care Attracts Businesses, but Not Many Doctors
    by Phil Galewitz, KFF Health News and Holly K. Hacker on 18/04/2024 at 09:00

    Most Medicare enrollees have two or more chronic health conditions, making them eligible for a federal program that rewards physicians for doing more to manage their care. It shows promise in reducing costs. But not many doctors have joined.

  • Paris Hilton Backs California Bill Requiring Sunshine on ‘Troubled Teen Industry’
    by Molly Castle Work on 17/04/2024 at 09:00

    Celebrity hotel heiress Paris Hilton is expanding her campaign for more public reporting on residential therapeutic centers’ use of restraints and seclusion rooms in disciplining teens, setting her sights on legislation in Sacramento and Washington, D.C.