• Probiotic prescriptions for premature babies to reduce disease risk
    on 27/09/2022 at 13:00

    Premature babies in neonatal units could be given personalized prescriptions of bacteria directly into their stomachs to improve health and reduce disease risk, new research has revealed.

  • Harms reporting is inconsistent across organ cancer guidelines
    on 27/09/2022 at 11:31

    A review of 33 organ-specific cancer screening guidelines has found that the reporting of harms related to screening tests and procedures is inconsistent across cancer types and at each stage of the screening process. The review is published in Annals of Internal Medicine.

  • Anti-TNF continuation after 24 weeks of pregnancy beneficial to persons with IBD, does not affect neonatal outcomes
    on 27/09/2022 at 11:31

    A 10-year emulation trial of pregnant persons with inflammatory bowel disease (IBD) has found that continuation of anti–tumor necrosis factor (anti-TNF) treatment after 24 weeks of pregnancy appears beneficial regarding IBD activity and prematurity, while not affecting neonatal outcomes and serious infections in the offspring. The findings are published in Annals of Internal Medicine.

  • Removing binding sites for an oncogene can slow down cancer cell growth
    on 27/09/2022 at 11:23

    Researchers focusing on the effects of the MYC oncogene have revealed new information about the factors that regulate the growth of cancer cells. MYC promotes the expression of genes that are important for cellular growth, and it is known to be overactive in more than half of all human cancers. However, there are no drugs currently available for inhibiting MYC function because its protein structure is not well suited for therapeutic targeting. Alternative option for preventing MYC activity would be to inhibit the function of the MYC target genes. In their recent study, the researchers of University of Helsinki belonging to Academy of Finland’s Center of Excellence in Tumor Genetics Research have identified target genes of MYC that are responsible for its growth promoting effects.

  • Researchers identify new model of Alzheimer’s as an autoimmune disease
    on 27/09/2022 at 11:21

    Scientists at the Krembil Brain Institute, part of the University Health Network, have proposed a new mechanistic model (AD2) for Alzheimer’s, looking at it not as a brain disease, but as a chronic autoimmune condition that attacks the brain.