Everyday life throws a whole range of emotional experiences our way, from exciting and relaxing moments to tense or gloomy encounters. Each experience is shaped by what’s present around us in the moment, the sensations our body is experiencing and our past experiences. This entire scene is set by the brain, which draws on these experiences of the past, organizing the information it gathers into mental maps that help us predict what might happen and respond appropriately to different situations.

A phase 2b clinical trial led by Mass General Brigham Heart and Vascular Institute researchers shows that a monoclonal antibody therapy called MAR001 can significantly reduce triglyceride levels within 12 weeks for patients with high triglyceride levels. Their results are published in the New England Journal of Medicine and were presented simultaneously at the American Heart Association’s annual meeting.

Researchers at the University of East Anglia (UK) have proposed an explanation for why some childhood tumors spread aggressively around the body despite having relatively few genetic faults. For years, experts believed cancers become more dangerous by accumulating genetic mutations that allow them to invade new tissues and evade treatment. But a new paper shows how childhood cancers may not always need extra mutations to spread.

A study led by cell biologist Dr. Arun Pal at the HZDR, in collaboration with research partners in Dresden and Rostock, has found that electromagnetic alternating fields can partially reverse key pathological changes in human nerve cells. The finding has been published in the journal Cells.

Using portable filters to reduce exposure to air pollution during sleep may stabilize the large spikes in blood sugar experienced by people with prediabetes, a condition in which sugar (glucose) levels are higher than normal, a new study shows.