New research from the University of Otago—Ōtākou Whakaihu Waka has uncovered another clue to potentially identifying Alzheimer’s disease early. Using data from the Dunedin Multidisciplinary Health and Development Study’s age 45 assessments, researchers investigated a specific biomarker in blood plasma, ptau181, which has been shown in other studies to be strongly associated with Alzheimer’s disease in later life.

Alzheimer’s disease begins to weave a web in the brain and remodel neuronal tissue 15 to 20 years before the first symptoms appear. From the time this happens, however, until the disease is diagnosed and, later, enters an advanced phase, it progresses along a continuum of changes to the brain. Now, an international team with Universitat Oberta de Catalunya (UOC) participation has developed a method for detecting variations in this continuum, which makes it possible to accurately assess the progression of dementia.

Researchers with the James P. Allison Institute at The University of Texas MD Anderson Cancer Center have discovered a new gene expression signature within tumors that can help identify patients with metastatic castration-resistant prostate cancer (mCRPC) who are more likely to experience lasting benefits from combined immunotherapy treatment.

Most people have experienced the feeling: switching from one task to another, only to find the brain momentarily stuck in the old mode of thinking. Sometimes, even after realizing a strategy no longer works, the mind keeps returning to it anyway.

Researchers at Wake Forest University School of Medicine found evidence of slowed aging from lifestyle behaviors like healthy eating and exercise as part of a major clinical trial.