Losing weight with lifestyle changes in an intensive behavioral weight loss program was associated with a decrease in risk factors for cardiovascular disease and Type 2 diabetes for at least five years—even if some weight was regained, according to a systematic review of research, published today in Circulation: Cardiovascular Quality and Outcomes.

There’s been a recent push in the U.S. to make naloxone—a fast-acting opioid antidote—available without a prescription. This medication has saved lives, but it’s less effective against powerful synthetic opioids, such as fentanyl. In an interesting twist, researchers are now looking to cannabidiol (CBD), a component of marijuana, as a possible alternative to the popular antidote. Today, a team reports compounds based on CBD that reduce fentanyl binding and boost the effects of naloxone.

Growing resistance to antibiotics and other antimicrobial treatments is a serious global healthcare challenge. A new study in Antibiotics demonstrates a method for tracking the spread of genes for antimicrobial resistance among bacterial populations over time. The new computational technique relies on the rapidly increasing availability of bacterial genetic sequences in public databases such as GenBank.

A University of Massachusetts Amherst nutrition scientist who has spent his career studying breast milk has demonstrated how beneficial microbes in the gut of infants use nitrogen from human milk to support pediatric nutrition and development.

North Carolina Gov. Roy Cooper on Monday signed a Medicaid expansion law that was a decade in the making and gives the Democrat a legacy-setting victory, although one significant hurdle remains before coverage can be implemented, thanks to a Republican-backed provision.