New research on a group of Australian preschoolers suggests more than 40% are dealing with an anxiety disorder.

When you’re an expert on the gut, you’re used to conversations others might shy away from. So a book on pooping and what can go wrong in the process is on brand for Trisha Pasricha, a second-generation gastroenterologist whose childhood was marked by matter-of-fact directness.

Scientists have identified a particular protein in the body that may influence the progression of alcohol-associated liver disease and drinking behavior. The protein aquaporin 9 (AQP9) helps liver cells absorb and excrete a byproduct of alcohol, which can be toxic to the body. The findings, published in Alcohol: Clinical and Experimental Research, point to AQP9 as a potential therapeutic target for the treatment of advanced liver disease and alcohol use disorder.

A growing body of research shows that diabetes can be stratified into five different subgroups. Researchers at Lund University have now investigated whether a person’s genetic predisposition to different diabetes subgroups can help assess the risk of developing coronary artery disease. The team created genetic risk scores and found that the scores for one subgroup could predict coronary artery disease, even before the onset of diabetes.

Women’s HRT patches can treat prostate cancer just as effectively as standard hormone injections—but with fewer of the worst side effects—according to a large UK trial published in the New England Journal of Medicine. The finding could change how men with prostate cancer that has spread beyond the gland are treated for years to come.