For women age 70 and over with a common form of breast cancer, determining “the right size” of treatment can be challenging, in part because clinicians have limited tools to guide individualized treatment decisions. In a study published today in Clinical Cancer Research, scientists at UPMC Hillman Cancer Center and the University of Pittsburgh School of Medicine found that a blood-based test may help guide treatment decisions for a carefully selected group of women age 70 and over who have estrogen receptor–positive breast cancer, who were considering endocrine (or hormone-blocking) therapy as the primary treatment and forgoing surgery and radiation.

Adverse childhood experiences and traumatic events experienced or witnessed at any point during one’s lifetime can sometimes prompt the emergence of some mental health disorders, such as post-traumatic stress disorder (PTSD) and complex PTSD (c-PTSD). Past studies suggest that these disorders emerge from epigenetic factors, or in other words, from changes in gene activity that occur in response to the environment or experiences.

Exercise. It can be hard for a lot of us to get started. Regardless of how you feel about physical activity, it comes with various benefits. One benefit of exercise that is not often recognized is its assistance in lowering cancer risk.

Researchers at Monash University, together with a multidisciplinary team of health care professionals and medication safety experts, have developed the first national consensus list of medicines with a high risk of harm in Australian residential aged care. Published in the Australasian Journal on Ageing, the study identified 15 high-risk medications or medication classes that require specialized monitoring in aged care settings. These medications carry a significant risk of serious harm or death if misused or used in error.

Twenty-five years into her diabetes and youth research, epidemiology professor Angela Liese and her team continue to increase our understanding of this uniquely vulnerable population. The team’s recent findings reveal that youth and young adults who have diabetes and experience food insecurity have higher rates of mental health symptoms, including disordered eating.